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About us

Welcome to the web site of our laboratory at National Research Tomsk Polytechnic University led by Dr. Roman Surmenev. The laboratory was established in 2011 and is focused on understanding fundamental studies and applied research in the world of biomaterials.

Join Our Team!

If you are an active, energetic person, who is interested in biomedical material science, additive technology and magnetron sputtering, seeks self-improvement and professional self-realization you can join our team!

If you want to work in a collaborative environment where opportunities are offered, skills are stretched and excellence is rewarded, you might be exactly what we’re looking for!

Specifically, our research involves design, fabrication and evaluation of novel materials and coatings for tissue regeneration, medical implants and devices. We actively explore medical applications of nanomaterials and nanotechnology. Feel free to explore! You can find more details about our research efforts, our research outputs, our team and how to join our projects.

Please explore the website to learn more about the ongoing projects in the laboratory and the scientists behind the biomaterials science. If you are interested in collaboration, please contact to our Team Leader - Dr. Roman Surmenev!
Our Team

Research output

Awards

Articles

Patents

Research area

Magnetron sputtering

Magnetron sputtering

In one direction our research group study the fundamental principles of RF-magnetron sputter deposition of calcium phosphate coating as an approach to enhance biocompatibility of metallic and polymer materials applied in regenerative medicine.

Due to the current trend of the population ageing the development of biomaterials for tissues regeneration plays a major role in the field of medical material science. Nowadays, the doctor should have a number of implant systems at his disposal allowing to choose the device for individual patient’s needs to solve any even the most difficult clinical problems. To achieve the favorable implant interaction with the living body the specified interface properties of devices should be created.

As it is considered the interaction between the implant and organism occurs by the aggression path. Human body interprets implant as a foreign substance and tries to get rid of it. The interaction between the cells and tissues with the biomaterials is strongly defined by the tissue-implant interface. The surface properties determine both the biological response to the implants and the material response to the physiological environment. Hence, surface engineering of biomaterials is aimed at modifying the material properties through changes in surface properties meanwhile maintaining the bulk properties of the implant. The application of a biocompatible coating to the implant is a well-documented strategy. Biocompatible coatings must be free from toxic substances, do not cause negative immune reactions, don’t degrade (or degrade in a predictable manner) in contact with living tissues, and show a high adhesion to the implant. Calcium-phosphates are proved to be a natural metabolite of bone. In the field of medical material science, there are numerous studies devoted to increasing of the biocompatibility and osteoinduction of metal implants using calcium phosphate coatings (CaP). Hydroxyapatite (HA, Ca10(PO4)6(OH)2) – is a typical example belonging to the family of CaP materials. As this material defines the bone matrix, it possesses a high biocompatibility.

Radio frequency (RF) magnetron sputtering method is used to obtain the functionally-graded HA thin films. Magnetron sputter deposition is a very attractive method due to the high adherence of the coating to the substrate material, the thickness uniformity of the deposited layer, and the ability to control the coating structure (amorphous or crystalline) and the Ca/P ratio by varying process conditions. Method allows to deposit coatings with predetermined features and to improve the performance of medical implants including devices with complex geometries. In order to develop coatings with additional functional properties there are some studies carried out in the direction of using the modified HA. In particular, we deal with HA material substituted with silver to obtain antibacterial effect and silicate ions to increase coating bioactivity.

Currently, there is no reliable information on the growth mechanisms of CaP based coatings during RF-magnetron sputter deposition. Generally, researchers focus only on the controlling of process parameters to optimize the coating properties in connection with biological studies without investigation of the fundamental aspects of the film growth. This fundamental understanding is the key approach for further technological improvements. This makes it necessary a detailed description of the different processes occurring at the substrate level and an in-depth characterization of the thin film properties. Only the combination of both thin film and plasma characterisation allows to elucidate the growth mechanisms.

Hence, the main objective is the investigation of the fundamental aspects of the deposition of HA coatings by means of RF-magnetron sputtering and the development of strategies to obtain coatings with tailored properties

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Additive manufacturing

Additive manufacturing

Formation of personalized implants with an individual form for each patient is a new step in the development of biomedicine. The ability to model implants of any shape and size, the functionality of the components and properties, price ratio in the production of single or small series of products, all of these advantages belong additive technology (AT), or more commonly known as the technology of 3-D printing.

In our work, we use a method of electron-beam melting which is one of the most advanced among the three-dimensional printing technology. It includes the distribution of the working material layer-by-layer and its melting under the influence of the electron beam. Metal implants prepared in this way can also successfully “to repeat” complex microstructure of bone, which improves the integration process of the implant and its long-term stability in the body.

In this case titanium alloy, Ti6Al4V powder is working material for electron beam melting because it is widely used in biomedicine for hard tissue replacement of dysfunctional due to high strength, light weight, good biocompatibility and corrosion resistance. However, we aim to create an even more improved biocompatibility of the surface by deposition of bioactive calcium phosphate coatings and antimicrobial silver nanoparticles. These modification methods already have proved themselves in the field of plasma technology and colloid chemistry.

To date, we carry out experimental and theoretical studies of the properties of the modified surfaces, including research of the wettability mechanisms biocomposites, the influence of the porosity and chemical composition of the surface on hysteresis, surface energy, the impact of the structure, chemical, phase composition and roughness parameters on the physical and mechanical properties (micro-hardness, Young's modulus) of the biocomposites.

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Magnesium implants

Magnesium implants

Advances in medical technology come with a large amount of materials that are currently under consideration for possible implantation into the human body. With the object to be compatible with the body these potential materials need do not cause any further harm. Biodegradable materials are dispelling the current stereotype in biomaterial science to research and produce only corrosion resistant materials. Especially, materials which consist of nutrients existing in the human body are high-potential expectants for this approach. The main point is that biodegradable implants and coatings can support tissue regeneration and healing in the process of material degradation and can gradually dissolve with replacement by natural tissue.

Biodegradable metals take priority over current biodegradable materials for example bioactive glasses, polymers or ceramics as applied to loads in body that require a higher tensile strength and a Young’s modulus that is closer to bone.

The magnesium has drawn great consideration in capacity of biodegradable material for bone joint replacement due to its similar mechanical properties with human bone, biodegradation and biocompatibility. By the way, the high degradation rate of magnesium delimitates its application as bioimplant materials. In the past decade, various approaches have been investigated to improve the degradation behaviour of magnesium. Development of biocompatible coatings and alloying are the most common methods that have been investigated. It has to be said, biocompatible calcium phosphate (CaP) has limelighted great attention in recent years as a coating material on magnesium and its alloys.

The development of biocompatible CaP coating on the surface of magnesium alloys is one of the way to control their degradation rate. Thick CaP coatings that were prepared by wet-chemical methods are well known. Nevertheless, wet-chemical methods of CaP coating deposition on the surface of magnesium alloys often is afflicted with weak adhesive strength. Currently, researchers are prone to establish a thin protective surface layers on the surface of alloys, which allows to keep the initial substrate topography and enhance the corrosion resistance. However, even by now, there is insufficient information on the corrosion resistance of these coatings. The RF magnetron sputtering is a preeminent method for deposition of pure HA. On top of everything else, a HA coating received by RF magnetron sputtering is well-adhered to the substrate.

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Our team

News

A student of the Institute of Physics and Technology, engineer of Technology Centre, Ekaterina Chudinova became a laureate of the scholarship of academician V. Nakoryakov.

This scholarship is assigned to young scientists for high results in research and is paid out by funds of the endowment fund TPU.
Scientific work of Ekaterina is devoted to the modification of the biostructure based on titanium alloys, manufactured by rapid prototyping technology and investigation of its properties.

http://news.tpu.ru/news/2017/06/06/27309/

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Won the competition at the international exhibition!

The “Titanium scaffolds for regenerative medicine” project has got the highest award at the international exhibition “High Technologies. Innovation. Investments» (HI-TECH) in St. Petersburg (Russia). The development of this project is carried out in the Center of Technology of the Tomsk Polytechnic University under the supervision of Maria Alexandrovna Surmeneva and Roman Anatolyevich Surmenev, as well as with participation of students, PhD students, and young scientists: Yevgeny Melnikov, Ekaterina Chudinova, Anna Ivanova, Mikhail Tkachev and Svetlana Gorodzha. We wish you all good luck and further success.

Our special acknowledgments to Dr. A. Koptug for his help and support in this project!

http://news.tpu.ru/news/2017/03/03/26823/

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National research Tomsk polytechnic university

Address : Russia, 634021, Tomsk, Lenin Avenue 43 (TPU educational building №3, street corner Usov and Lenin Avenue, Rm. 118)
Owner : Dr. Roman A. Surmenev Phone : 8(3822) 563-451 Mobile : +7 903 953 09 69